To the Editor Dr Angus outlined a perspective in which randomized clinical trials (RCTs) are fused with “big data,” referring to increasing digitization of patient and health care information in electronic health records (EHRs).1 As a member of the work group on research data in relation to EHRs in our medical center, I was concerned about the optimistic expectations of using EHRs as a major source of information for clinical research.
Opmeer BC. Electronic Health Records as Sources of Research Data. JAMA. 2016;315(2):201-202. doi:10.1001/jama.2015.15419