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This volume has been prepared by the authors as an immediate aid to the puzzled physician in arriving at a diagnosis of disease. Indeed, the suggestion is made in the preface that the book is to be used as a quick reference while the patient is being prepared for examination or while he is dressing after the examination. It is arranged with special reference to the regions of the body and to the symptoms associated with those regions. For example, the single symptom "headache" occupies the first twelve pages of the book; it is discussed with relation to the portion of the head concerned and the possible disease conditions that might produce such a headache. The work is not readable in the ordinary sense of that term; it is strictly a work of reference, largely in outline form. It is not so much a work of diagnosis as of differential
Symptom Diagnosis, Regional and General.. JAMA. 1927;89(1):52. doi:10.1001/jama.1927.02690010052035