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In Reply Our Viewpoint concerned the inappropriate overdiagnosis of CKD in older adults using non–age-calibrated eGFR thresholds, as recommended by current guidelines,1 and the potential adverse effect of placing a label of CKD on persons older than 65 years entirely on the basis of the discovery of an eGFR of 45 to 59 mL/min/1.73 m2 in the absence of proteinuria or other signs of kidney injury.
Glassock RJ, Delanaye P, El-Nahas M. Managing Chronic Kidney Disease in Older People—Reply. JAMA. 2016;315(3):307-308. doi:10.1001/jama.2015.15999