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Comment & Response
January 19, 2016

Managing Chronic Kidney Disease in Older People—Reply

Author Affiliations
  • 1Geffen School of Medicine, University of California, Los Angeles, Laguna Niguel
  • 2Department of Nephrology, Dialysis, and Transplantation, University of Liege, Liege, Belgium
  • 3Sheffield Kidney Institute, Global Kidney Academy, Sheffield, England
JAMA. 2016;315(3):307-308. doi:10.1001/jama.2015.15999

In Reply Our Viewpoint concerned the inappropriate overdiagnosis of CKD in older adults using non–age-calibrated eGFR thresholds, as recommended by current guidelines,1 and the potential adverse effect of placing a label of CKD on persons older than 65 years entirely on the basis of the discovery of an eGFR of 45 to 59 mL/min/1.73 m2 in the absence of proteinuria or other signs of kidney injury.

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