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Comment & Response
January 26, 2016

Epinephrine Administration and Pediatric In-Hospital Cardiac Arrest

Author Affiliations
  • 1Sydney Medical School Nepean, University of Sydney, Sydney, Australia
  • 2Nepean Hospital, Sydney, Australia

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2016;315(4):416-417. doi:10.1001/jama.2015.16449

To the Editor The study by Dr Andersen and colleagues1 found an association between delayed administration of epinephrine and poorer survival rates after in-hospital pediatric cardiac arrest.

There are at least 3 possible scenarios for delivering epinephrine: the patient might already have a functioning cannula or central line, venous access might be attempted during resuscitation, or epinephrine might be delivered by intraosseous injection. Epinephrine can be given quickly and reliably by intraosseous injection, but clinicians could preferentially attempt intravenous administration first.

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