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Comment & Response
January 26, 2016

Epinephrine Administration and Pediatric In-Hospital Cardiac Arrest—Reply

Author Affiliations
  • 1Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
  • 2Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
  • 3Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
JAMA. 2016;315(4):417. doi:10.1001/jama.2015.16464

In Reply We do not have data on whether the first epinephrine bolus was administered by an intravenous or intraosseous injection. The variable we used for assessment of epinephrine administration included both intravenous and intraosseous administration but did not distinguish between the two.

Similarly, we did not have reliable and consistent data on whether the patient already had functioning vascular access at the time of the cardiac arrest.

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