Diffuse osteolytic lesions of the skeletal system are often among the clinician's most difficult diagnostic problems. Even microscopic examination of biopsy material may be inconclusive for exact diagnosis. We have recently seen a patient whose widespread lesions confused several physicians in other localities as well as ourselves. The correct diagnosis was established only by skeletal biopsy. Because we have found in the literature no clinical description of a similar case, we feel justified in calling the entity to the attention of the profession in order that it may be considered in the differential diagnosis of patients who suffer with multiple skeletal lesions, osteolytic in character.
REPORT OF CASE
R. P., a white man aged 21, was referred to us by Dr. Warfield M. Firor for diagnostic study. The patient's medical history was free of all but minor illnesses until his skeletal difficulty was accidentally brought to light. Birth
Pierson JW, Farber G, Howard JE. MULTIPLE HEMANGIOMAS OF BONE, PROBABLY CONGENITAL. JAMA. 1941;116(19):2145–2148. doi:10.1001/jama.1941.62820190001007