In the fall of 1925 I1 ascertained the end-results of a small series of gallbladder operations and found that 84.4 per cent of the stone cases were apparently cured, whereas only 70 per cent of the noncalculous group were without symptoms. About the same time Whipple2 found in a similar study that 89.4 per cent of the calculous cases and 76.6 per cent of the noncalculous cases were cured by cholecystectomy. The difference in the percentage of cure was almost identical in the two series.
The liability of frequent recurrence of symptoms after operation on the noncalculous gallbladder has been long known, and in an early paper Stanton3 found only 46 per cent of cures in a series of ninety-nine cases, in ninety-two of which cholecystostomy had been performed. But in 1914, W. J. Mayo4 noted that simple drainage will not cure the majority of these
MULLER GP. THE NONCALCULOUS GALLBLADDER. JAMA. 1927;89(10):786-789. doi:10.1001/jama.1927.02690100048013