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Skin Salt Solution Test in Edema
In submitting a report on the McClure-Aldrich salt solution test, Dr. H. Povoa pointed out that nowadays it is no longer the fashion to speak of edema but of edemas, according to the type, the originating and contributory causes, the pathogenic mechanism, renal, cardiac, acute or chronic toxiinfectious, nervous, metabolic, and the like. Different authors have stressed the disappearance of capillary permeability, loss of balance between arterial and venous pressure, hydremia, vasomotor influence of the nervous system, trophic rôle of the motor system and other changes. Povoa studied the value of the McClure-Aldrich skin test in several groups. In eleven normal subjects the resulting wheal disappeared in between forty-five and sixty-five minutes. In five cases of hydropigenous nephritis the test showed a disappearance time of twelve, fourteen, twenty, seven and twelve minutes. The time varied according to the degree of the edema. In ten
RIO DE JANEIRO. JAMA. 1927;89(10):804-805. doi:10.1001/jama.1927.02690100066023