My purpose in this paper is to describe a bladder lesion of specific etiology which may develop many months after an apparently successful application of radium to a carcinoma of the uterus.
Urologists probably will be called on to treat an increasing number of patients for this condition, in which the history, symptomatology and cystoscopic appearance strongly suggest carcinoma of the bladder, but no tumor is present. If the approved methods of treating carcinoma should be employed in these cases, it is likely that the results would be disastrous.
During the past year three elderly women have been referred to me because they were suffering from pyuria, dysuria and hematuria of considerable degree. The remote histories were of no especial significance except that each patient had been treated with radium for carcinoma of the uterus. The location of the primary tumor in two of the patients was the cervix; in
DEAN AL. ULCERATION OF THE URINARY BLADDER AS A LATE EFFECT OF RADIUM APPLICATIONS TO UTERUS. JAMA. 1927;89(14):1121-1124. doi:10.1001/jama.1927.02690140017005