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On the basis of mental test, Kornfeld finds that glandular therapy has a beneficial influence on the mental as well as the physical development of children with hypothyroidism. However, he warns that a parallel improvement does not occur in all cases. Characteristic of the neurologist defending other drugs, he emphasizes correctly that the disrepute into which thyroid therapy has fallen is due to its abuse. Of greatest importance in the glandular treatment of hypothyroidism in children is the correct dosage as determined by Nobel and the necessity for its earliest possible and uninterrupted administration. This is half the battle. The rest consists of education, without which no medical management proves of much avail. In children in their teens as well as in earliest childhood there remains an injury to mental capacity, a slowness of association, and a lack of active attention with a consequent poverty of ideas. If such children
Ueber die geistige Entwicklung hypothyreotische Kinder bei spezifischer Behandlung.. JAMA. 1927;89(14):1172. doi:10.1001/jama.1927.02690140068035