Although the syndrome of paroxysmal hypertension due to a chromaffin tumor of the adrenal gland has been thoroughly reviewed by several authors,1 it remains a rare disease. Thus in 1939, seventeen years after Labbé, Tinel and Doumer2 gave the first clinical description, Eleanor Humphreys3 could find in the literature only 103 cases. Many of the reports represent pathologic studies, accidental postmortem observations or, in cases in which the diagnosis had been made, postoperative death. Hence since 1929, when Pincoffs4 reported the first case in which a successful operation followed a correct diagnosis, there have been relatively few reports. For these reasons it is believed that the following detailed case history is of interest.
REPORT OF CASE
E. C., a woman aged 49, was admitted to the private pavilion on Feb. 5, 1940 complaining of attacks of "blood pressure."Her father had died at the
Heath FK, Cahill GF, Atchley DW. PHEOCHROMOCYTOMACORRECT DIAGNOSIS AND SUCCESSFUL OPERATION. JAMA. 1941;117(15):1258–1260. doi:10.1001/jama.1941.72820410003010a