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Article
November 5, 1927

CONSIDERATIONS IN CIRRHOSIS OF THE LIVER

Author Affiliations

ROCHESTER, MINN.
From the Division of Medicine, Mayo Clinic and the Mayo Foundation.

JAMA. 1927;89(19):1590-1597. doi:10.1001/jama.1927.02690190028009
Abstract

The medical student of two decades ago carried with him on leaving his alma mater a very imperfect knowledge of cirrhosis of the liver. He was altogether inadequately equipped to grapple successfully with the problems of cirrhosis as they are encountered in the practice of medicine. He had acquired a fair conception of Laënnec's1 cirrhosis. He was familiar with the textbook picture of Hanot's2 cirrhosis (and is probably still looking for his first case of this disease). He was aware of the existence of hemachromatosis or bronze diabetes. He was taught to be on the qui vive for syphilis of the liver but was quite uncertain as to its clinical manifestations. Since those days considerable progress has been made in the study of the anatomy and physiology of the liver; new diagnostic methods have been introduced, functional tests have been developed, and it would appear that we are

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