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The fifth edition of this book appeared in 1923. The present edition has been expanded to include modern developments. New sections have been added on many subjects in which particularly therapy has advanced; moreover, therapeutics has been expanded to include also prophylaxis, general treatment and psychotherapy. As the volume is now made up, its pages include more than 1,200 devoted to therapeutics and the remaining 170 to laboratory technics, dosages, materia medica, and a considerable amount of miscellaneous tabular data and similar information. In the section devoted to therapeutics, disease and disease conditions are alphabetically arranged. Under each heading there is a definition, followed by discussions of etiology, diagnosis, symptoms and treatment. There are many useful tables of differential diagnosis.
In the compilation of the work, most of the leading text-books on medicine and also leading textbooks in each of the specialties have been consulted. Dr. Bernard Fantus, professor of
The Merck Manual of Therapeutics and Materia Medica: A Source of Ready Reference for the Physician. JAMA. 1934;103(1):65. doi:10.1001/jama.1934.02750270067030