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Here is a thorough digest of the treatment of human trypanosomiasis with tryparsamide. The author was closely identified with this work long before the introduction of tryparsamide to the medical profession. The work with this preparation has been done in a highly scientific manner. This monograph attests to the care with which Dr. Pearce has pursued her studies. Eight years has elapsed since the tryparsamide treatment of African sleeping sickness was instituted in the Belgian Congo. As the author points out, in the intervening years the use of the drug has constantly increased throughout tropical Africa where trypanosomiasis occurs, and considerable literature has accumulated on the subject. The monograph includes a review of the available records of cases that bear on tryparsamide therapy, the total number of cases considered being 1,848. From her critical analysis of the data Dr. Pearce concludes that tryparsamide is an efficacious drug for the treatment
The Treatment of Human Trypanosomiasis with Tryparsamide: A Critical Review.. JAMA. 1931;96(12):974. doi:10.1001/jama.1931.02720380062038