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March 28, 1931


JAMA. 1931;96(13):1089. doi:10.1001/jama.1931.02720390099011

Negative results in research are not nearly so exciting as positive, but they are important and, unfortunately, seem to have a higher average of reliability than most of the results reported as positive. A particularly important report of negative results has recently been published under the title of the etiology of lymphadenoma, a summary of six years' researches, by C. C. Twort,6 pathologist to the Manchester Committee on Cancer. By lymphadenoma is meant what most American physicians usually call Hodgkin's disease and what Germans often designate as lymphogranulomatosis, one of many striking illustrations of the distressingly confused conditions of medical nomenclature. The importance of the report lies in the fact that it is based on an extremely careful study by many methods on a large amount of material; sixty-one cases positively identified by the presence of typical "lymphadenoma giant cells," and twenty-one cases either probably or possibly lymphadenoma. Most

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