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Comment & Response
June 14, 2016

Ultrasound vs Angiography for Drug-Eluting Stent Implantation

Author Affiliations
  • 1Interventional Cardiology, Medstar Washington Hospital Center, Bethesda, Maryland
JAMA. 2016;315(22):2469. doi:10.1001/jama.2016.1371

To the Editor Dr Hong and colleagues1 reported the results from the IVUS-XPL trial on the effect of IVUS-guided vs angiography-guided everolimus-eluting stent implantation. The rate of major adverse cardiac events was lower in the IVUS-guided group vs the angiographic group, with lower rates of target vessel revascularization but not death or myocardial infarction. Ischemia-driven revascularizations were measured with quantitative coronary angiography and defined as a diameter stenosis of 50% plus symptoms or a diameter stenosis of greater than 70% irrespective of symptoms.

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