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Infection with HIV may be associated with accelerated cellular aging, according to a new study in which researchers analyzed DNA methylation patterns of men with HIV infection (Gross AM et al. Mol Cell. 2016;62:157-168). The study provides a possible explanation for why people with HIV who take antiretroviral medications often develop age-related conditions such as cardiovascular disease, hypertension, bone fractures, and renal failure years earlier than those who are uninfected (Guaraldi G et al. Clin Infect Dis. 2011;53:1120-1126).
Jacob JA. Men With HIV Age Faster According to DNA Methylation Study. JAMA. 2016;316(2):135-136. doi:10.1001/jama.2016.7001