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News From the Food and Drug Administration
June 21, 2016

Antipsychotic Drug May Cause Impulse-Control Problems

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Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2016;315(23):2514. doi:10.1001/jama.2016.7384

An FDA safety announcement has warned that the antipsychotic drug aripiprazole has been linked with compulsive or uncontrollable urges to gamble, binge eat, shop, or have sex (

Agency officials said the urges were reported to have stopped when the medication was discontinued or the dose was reduced. “These impulse-control problems are rare, but they may result in harm to the patient and others if not recognized,” they explained in a statement.

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