This communication concerns itself primarily with a discussion of hyperparathyroidism as a cause of urinary calculi. In the course of our remarks, certain other possible etiologic factors will be dealt with.
Next perhaps to malignant disease, urinary lithiasis presents one of the most difficult problems confronting the urologist. Until this question is answered he finds himself occupied in the more or less unproductive occupation of discovering and removing stones from the kidney, ureter or bladder. We do not hesitate to say that no hypothesis as to etiology yet presented can be defended from every line of attack, nor does it matter that certain experimental studies have resulted in stone formation. What may be true in the laboratory does not necessarily follow in the clinic. Even parathyroid disease, which is found to be the apparent etiologic factor in at least 10 per cent of cases, brings up questions that in the
BARNEY D, MINTZ ER. SOME NEWER CONCEPTIONS OF URINARY STONE FORMATION. JAMA. 1934;103(10):741-743. doi:10.1001/jama.1934.02750360017008