If the problem of acute nephritis were limited in its scope to the acute episode, the subject would be a comparatively simple one. But this is not the case. While it is not unanimously believed that chronic glomerular nephritis evolves from an unhealed acute attack, this is an opinion widely held. During the past ten years observations by many investigators1 have been made on the relationship of the acute phase to the chronic form, and there seems to be sufficient evidence to substantiate the assumption that chronic glomerular nephritis is a remote consequence of acute nephritis which failed to heal completely.
There are many obstacles in establishing the proper correlation between the acute and the chronic stage of nephritis. Among them is the difficulty of convincing the patient of the need of reexamination in the years after the acute phase is over and before symptoms of chronic nephritis begin.
MURPHY FD, PETERS BJ. TREATMENT OF ACUTE NEPHRITISTHE IMMEDIATE RESULTS AND THE OUTCOME TEN YEARS LATER IN EIGHTY-NINE CASES. JAMA. 1942;118(3):183–189. doi:10.1001/jama.1942.02830030001001