It is well recognized today that infections of the upper lip—particularly of the carbuncular type—are always to be considered most seriously; and furthermore that in the most virulent infections no form of treatment has proved efficacious in even a bare majority of instances. The superficial infections of the upper lip and adjacent structures on the lateral portion of the nose as a rule resolve without serious results; but the deeper infections, particularly in the upper lip, wherein the subcutaneous tissues become involved—the area in which the veins lie—are far too often followed by a fatality as the result of a septic cavernous sinusitis and meningitis.
It is practically impossible, at present, to state in the early stages of an infection of the upper lip how far the process will proceed; and it is well known that the most serious appearing infections have resulted in recovery, with or without good treatment,
ROEDER CA. LIGATION OF THE ANGULAR VEIN IN INFECTIONS OF THE UPPER LIP. JAMA. 1928;90(4):272-273. doi:10.1001/jama.1928.02690310024008