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This is a review of the available literature and a contribution to a subject encountered commonly enough but concerning which only too much is obscure. The author covers completely a clinical study of this symptom complex. He discusses its relationship to disturbances of the autonomic nervous system, endocrine disorders with which he thinks it commonly associated, and other functional diseases especially those of vasomotor type, and he cites many examples of its occurrence with organic disease. Atypical forms are well illustrated with case reports. He has little to add to previous knowledge of the etiology but has some engaging ideas in his consideration of the functional pathology of acrocyanosis. Any one who wishes to acquire a working knowledge of the condition will find this paper an excellent single source. The bibliography is extensive, including more than 300 references to European and American publications. The student of vascular diseases will find
Les acrocyanoses: Troubles vasculaires cutanés d'origine nerveuse végétative ou centrale.. JAMA. 1931;96(15):1255. doi:10.1001/jama.1931.02720410065038