Aberrant pancreatic tissue was first observed by Klob in 1859. Faust and Mudgett1 have recently reviewed the reported cases and added 1 of their own, bringing the total to 370. Apparently, through some error in embroyologic development, pancreatic tissue may develop in various ectopic sites separate from the normal pancreatic anlage. It has been found most frequently in the stomach, duodenum and jejunum, fairly often in the ileum and Meckel's diverticulum and rarely in the gallbladder, omentum and mesentery.
Seldom of clinical importance, the gland tissue is usually an incidental finding at surgical intervention or autopsy. It may, however, be the site of inflammation and ulceration necessitating surgical removal, and in the ileum the condition has been responsible for intussusception. Roentgenologically it may produce a filling defect simulating a polyp or a malignant growth. The case to be reported is of interest in exhibiting definite symptoms of hyperinsulinism which
Smith FG. ABERRANT PANCREATIC TISSUE WITH HYPERINSULINISM. JAMA. 1942;118(6):454–455. doi:10.1001/jama.1942.62830060001008