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In this volume Lewis not only presents the results of his investigation into the responses of the vessels of the skin to various stimuli, and the mechanism of the response, but provides a reference work which should stimulate research and afford a firm foundation for further investigation. A proper clinical interpretation of the phenomenon observed in the vascular responses of the vessels of the skin cannot be had without an accurate knowledge of the underlying mechanism, and such a basis the author has afforded to the clinician. The opening chapters are concerned with the anatomic background and the methods of study. The reactions to various stimuli are then considered. The white reaction, following a light stroke on the skin, is shown to result from contraction of the minute vessels. When the skin is stroked more firmly with a blunt instrument, a red reaction follows along the line of pressure. When
The Blood Vessels of the Human Skin and Their Responses.. JAMA. 1928;90(4):315-316. doi:10.1001/jama.1928.02690310067037