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September 29, 1934

Diseases Peculiar to Civilized Man: Clinical Management and Surgical Treatment

JAMA. 1934;103(13):1017. doi:10.1001/jama.1934.02750390061029

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Among the diseases which occur particularly in civilized human beings and which apparently are not found in savages or in the lower animals are peptic ulcer, hyperthyroidism and neurocirculatory asthenia. In considering their causation, Dr. Crile traces the development of the human brain from the lowest form to the highest and elucidates his belief that the diseases mentioned belong to the group of kinetic diseases, which are diseases of pathologic physiology bred in our phylogeny, in which there is a sustained abnormally high activity of the entire brain and suprarenal sympathetic system. He considers the development of the suprarenal glands and the suprarenal sympathetic system and then takes up each of the diseases mentioned, supplying case histories and indicating the value of suprarenal denervation as a means of control. There is also a section devoted to epilepsy and diabetes, including case histories of the method as applied to these conditions,

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