To the Editor Dr Gerber and colleagues assessed the association between antibiotic exposure during the first 6 months of life and childhood weight gain and concluded that there was no association.1 However, there was a significant difference in weight gain in children exposed to any antibiotic in the first 24 months of life (P = .001). The subanalyses showed that this difference was significant in children who received only 1 antibiotic course (P = .01) but was greater in those who received 2 courses (P = .02) and even greater in those exposed to 3 or more courses (P = .002). Can the authors comment on these findings and explain why they did not consider these significant differences in their discussion?
Esposito S. Early Antibiotic Exposure and Childhood Weight Gain. JAMA. 2016;316(5):541. doi:10.1001/jama.2016.7300