Sollmann,1 in discussing the action of atropine, says: "Ordinary therapeutic doses relax the intestines in man and rabbits (Katsch, 1913; Hirz, 1913). In cats, they may increase peristalsis (Magnus). It is conceivable that this also occurs in man in some conditions."
REPORT OF CASE
A woman, aged 30, the wife of a physician, was referred to me after the hay-fever season. She had sneezed excessively all the year, had been troubled with constipation and sour stomach for a month, and for three nights had had a dry, tickling cough. Nothing abnormal was found on physical examination: the sinuses were clear and the blood and urine normal. She was given magnesia and 15 drops of belladonna, three times a day, and promptly developed diarrhea with cramping. The magnesia was stopped without influencing the diarrhea. When the belladonna was stopped, the diarrhea and cramping disappeared over night. When
Allan W. ATROPINE DIARRHEA. JAMA. 1928;90(7):540. doi:10.1001/jama.1928.92690340001017