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Article
February 18, 1928

ATROPINE DIARRHEA

Author Affiliations

Charlotte, N. C.

JAMA. 1928;90(7):540. doi:10.1001/jama.1928.92690340001017
Abstract

Sollmann,1 in discussing the action of atropine, says: "Ordinary therapeutic doses relax the intestines in man and rabbits (Katsch, 1913; Hirz, 1913). In cats, they may increase peristalsis (Magnus). It is conceivable that this also occurs in man in some conditions."

REPORT OF CASE  A woman, aged 30, the wife of a physician, was referred to me after the hay-fever season. She had sneezed excessively all the year, had been troubled with constipation and sour stomach for a month, and for three nights had had a dry, tickling cough. Nothing abnormal was found on physical examination: the sinuses were clear and the blood and urine normal. She was given magnesia and 15 drops of belladonna, three times a day, and promptly developed diarrhea with cramping. The magnesia was stopped without influencing the diarrhea. When the belladonna was stopped, the diarrhea and cramping disappeared over night. When

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