[Skip to Content]
[Skip to Content Landing]
April 11, 1942


JAMA. 1942;118(15):1317. doi:10.1001/jama.1942.02830150053027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  In Queries and Notes in a recent issue of The Journal (February 14, p. 567) one reads the reply to the disturbing question concerning the safe concentration of sodium sulfathiazole when used in medicating the nasal mucosa. As was so well stated, sodium sulfathiazole is not free of undesirable reactions because of the irritating properties associated with its alkalinity. Aqueous solutions of sodium sulfathiazole vary in pH from 10 to 11 and may become yellow on standing, especially when unprotected from daylight. To obviate the strong alkalinity, irritating properties and deterioration of such solutions, we have dissolved various sulfonamides in propylene glycol (Modern Hospital57:106 [July] 1941; J. Indiana M. A., to be published in April). The most useful of these propylene glycol preparations have been a 3 per cent solution of sulfathiazole, a 3 per cent solution of sulfapyridine and a 10 per cent

First Page Preview View Large
First page PDF preview
First page PDF preview