March 17, 1928


JAMA. 1928;90(11):868-869. doi:10.1001/jama.1928.02690380052024

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Streptothrix Leproides in Leprosy  Drs. J. M. Gomes and D. do Pateo, Jr., have reported to the São Paulo Biologic and Health Society their further work on complement fixation with defatted Streptothrix leproides in leprosy. This test, while valuable for diagnostic purposes, has still more significance in prognosis and treatment. In recent cases it demonstrates the existence of an infection before symptoms have appeared. A strong reaction invariably points to a serious condition, in which treatment will prove either ineffectual or harmful. A positive result may express the existence of immunity rather than latent infection. In early cases or formes frustes the test often proves negative.

Hemolytic Complement  Dr. E. Vaz has called attention, before the São Paulo Biologic and Health Society, to an uncommon source of error in titrating hemolytic serums. It consists in the presence of hemolysins in the guinea-pig against the sheep cells. The striking feature in

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