In Reply In response to Dr Hursitoglu, we found that the urinary sodium to potassium excretion ratio was not significantly associated with CVD in our study (P for trend = .11). This is likely due to the lack of an inverse association between urinary potassium and CVD among patients with CKD. We additionally adjusted for urinary potassium excretion in a multivariable model and the results were not significantly changed (Table).
Mills K, He J. Sodium Excretion, Cardiovascular Disease, and Chronic Kidney Disease. JAMA. 2016;316(10):1112-1113. doi:10.1001/jama.2016.11558