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May 9, 1931


JAMA. 1931;96(19):1625. doi:10.1001/jama.1931.02720450067014

It is probably not unfair to conclude that the empirical treatment of epilepsy in children has in recent years advanced beyond the scientific interpretation of the methods in successful use. The dependence on drugs for the relief or prevention of the distressing seizures has been supplemented, if not entirely replaced, by what may be termed physiologic procedures. The practice in this field is changing. Fasting was the earliest of the "drugless" forms of treatment to win attention.1 This was followed by the use of diets relatively poor in carbohydrates and rich in fats—a method leading to the development of ketonemia.2 Indeed, the ketogenic regimen seems to have attained considerable vogue in the management of epilepsy in childhood.

McQuarrie3 has ventured to introduce a therapeutic regimen based primarily on the principle of dehydrating the patient. According to him there appears to be a tendency for the epileptic subject

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