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December 29, 1934


JAMA. 1934;103(26):2016-2021. doi:10.1001/jama.1934.02750520018005

This is a preliminary communication based on a review of six private cases1 that came to surgical exploration in the last six years. In four of these the operation was performed by Dr. A. A. Berg and the pathologic examination was made by Dr. Paul Klemperer at the Mount Sinai Hospital. All these cases were finally diagnosed nonspecific ulcerative granulomatous inflammation of the terminal ileum according to the criteria presented by Crohn and his collaborators in 1932.2 In the remaining cases operation was done elsewhere and before the term "regional (terminal) ileitis" was introduced in the literature. Nevertheless, these descriptions also agree on the presence of ileac thickening and ulceration, and on the absence of new growth, tuberculosis and other known specific inflammation or tumefaction. It therefore seems fair to assume, at least for the purpose of this preliminary communication, that a homogeneous group of cases is being

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