July 11, 1942


Author Affiliations

From the Department of Obstetrics and Gynecology, State University of Iowa College of Medicine.

JAMA. 1942;119(11):872-874. doi:10.1001/jama.1942.02830280018005

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During the sixteen years between Jan. 1, 1926 and Dec. 31, 1941, 80 eclamptic patients were observed and treated at the University Hospital. Thirty-seven women were admitted in the convulsive stage, and 43 suffered the seizures after admission; all but 13 of the latter were admitted because of toxemia. Throughout the series, eclampsia was viewed as a medical condition and treatment followed a fairly consistent pattern. This communication deals with the results obtained and involves a discussion of the lessons learned by the experience.

TREATMENT EMPLOYED  The essence of therapy revolves around the clinical observation that eclamptics generally do not have convulsions when the respirations are less than 14 to 16 per minute and the deduction therefrom that there is some relationship between the respiratory exchange and the appearance of the convulsive episodes. Heavy sedation was therefore employed, and the dosage was regulated solely by the effect on the respiratory

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