May 16, 1931

The Laboratory Mouse: Its Origin, Heredity, and Culture.

Author Affiliations

By Clyde E. Keeler, Sc.D., Research Fellow of the Howe Laboratory, Harvard Medical School. Cloth. Price, $1.50. Pp. 79. Cambridge: Harvard University Press, 1931.

JAMA. 1931;96(20):1725. doi:10.1001/jama.1931.02720460071039

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The mouse has become a most valuable laboratory animal. "The teacher of zoology uses variations of the house mouse to demonstrate the laws of heredity, the biological investigator employs them for physiological and genetic studies, the advanced medical man uses them as media in which to culture disease germs or for pathological tests as in the production of sera, and the fancier prizes them for their aesthetic appeal." The important rôle of the mouse in the study of the problems of cancer merits especial emphasis. This little book presents useful information, not heretofore assembled, on the origin, history, distribution, development, hereditary transmission of variations, and methods of breeding of the mouse. The larger part of the book deals with the unit characters and inheritance, normal and abnormal, of the house mouse. The chapter on breeding mice is of practical interest. The book will interest all who use mice in their

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