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July 18, 1942

Neural Mechanisms in Poliomyelitis

JAMA. 1942;119(12):984. doi:10.1001/jama.1942.02830290064031

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Recent important studies on poliomyelitis which have been carried on in the department of anatomy at the Johns Hopkins School of Medicine have been summarized in this volume. They deal largely, as the title suggests, with neuropathology, but the author and the reader cannot help but be drawn into a consideration of the wider implication of their observations. Consequently the book is not to be regarded as a neuroanatomic treatise, for (with certain recognized limitations) it is concerned with the whole problem of the pathogenesis and routes of infection in poliomyelitis in the clinical as well as the experimental disease. In other words, as T.M. Rivers points out in his foreword of this volume, the technic presented is that of the "neurobiologist." Essentially the experiments deal with the anatomic distribution of poliomyelitis lesions which have been experimentally produced within the central nervous system under a variety of different conditions; but

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