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May 19, 1928


JAMA. 1928;90(20):1628-1629. doi:10.1001/jama.1928.02690470034014

It has long been known that the volume of urine passed is greater in the recumbent than in the standing position.1 One cannot make any dependable deductions from this fact with reference to the effect of posture on the renal elimination of substances other than water. The kidney function involves a complex mechanism in which filtration in the glomeruli and reabsorption in the tubules interact to modify the final product, the urine eliminated. In illustration of this statement are the conclusions of White, Rosen, Fischer and Wood2 that urea, sulphate and phosphate are in part filtered through the glomeruli and in part secreted by the tubules; that the rate of filtration across a glomerular membrane is determined not only by the mean glomerular capillary pressure but also by the extent to which the application of pressure is pulsatile; that the greater urine flow in the recumbent position is due

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