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January 26, 1935


Author Affiliations

From the Department of Internal Medicine, University of Cincinnati College of Medicine, and the Vascular Disease Clinic, Cincinnati General Hospital.

JAMA. 1935;104(4):297-301. doi:10.1001/jama.1935.02760040029007

The importance of the concept of cardiovascular disease as a clinical entity is fully understood today. Emphasis has been placed, and properly so, on the recognition of cardiac abnormalities of various types. Recently the necessity of obtaining information as to the condition of the vascular tree has begun to be stressed. It is not believed today that arteriosclerosis is merely an expression of aging of the arteries. As Aschoff1 has said, "Arteriosclerosis is not merely a change or transformation attending the process of aging; it is not a mere infirmity of old age, but rather a disease of the vessels manifesting itself mainly during senescence." The clinical recognition of arteriosclerosis thus becomes a matter of import, because the type and the degree of arteriosclerosis present in a given individual have distinct prognostic significance. Any method of clinical examination that gives reliable information as to the condition of the vascular

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