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JAMA Diagnostic Test Interpretation
October 18, 2016

Thyroid-Stimulating Hormone in the Evaluation of Subclinical Hypothyroidism

Author Affiliations
  • 1Division of Metabolism, Endocrinology and Diabetes, University of Michigan, Ann Arbor
  • 2Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
  • 3Associate Editor, JAMA
JAMA. 2016;316(15):1592-1593. doi:10.1001/jama.2016.9534

A 62-year-old woman presented with a 6-month history of hair thinning, itchy scalp, and cold sensitivity. She reported no fatigue, depression, memory problems, dry skin, or constipation. She had hyperlipidemia for which she took fish oil and red yeast rice extract. Heart rate was 80/min and body mass index was 31 (calculated as weight in kilograms divided by height in meters squared). Physical examination demonstrated a thyroid gland of normal size and consistency without palpable nodules. Deep tendon reflexes were normal. Her laboratory values are reported in the Table.

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