Fluids for venoclysis are now dispensed in glassware, which will fracture when handled roughly or when the contents are frozen. It was deemed advisable, for reasons unnecessary to record here, to have a venoclysis unit devoid of these objections.
Distilled water and various solutions for intravenous use may be packed in properly fabricated enamel lined tin cans. However, the solutions are not readily evacuated from the cans without risk of contamination, and the duration of the reliability of solutions so packed is relatively short because corrosion cannot be prevented to an extent that renders the method free from danger.
To obviate these difficulties, it was necessary to find a unit which was resistant to corrosion and which could be placed in a can. Various types of rubber bags and plastics were first employed, but when the package, packed under vacuum, was sterilized the solutions became contaminated, as evidenced by the
Ivy AC, Harris SC. A VENOCLYSIS UNIT RESISTANT TO FREEZING. JAMA. 1942;119(17):1414-1415. doi:10.1001/jama.1942.72830340001008