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February 16, 1935


JAMA. 1935;104(7):589. doi:10.1001/jama.1935.02760070071031

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A complete survey of the abnormalities occurring in cell division is contained in this monograph. The interest in the subject lies not only in the biologic aspect in that mutations are now being produced in large numbers in the fruit fly Drosophila by irradiation but also because it is undoubted that the action of x-rays, radium, cathode rays and ultraviolet rays is in part at least on the division mechanism of the cells. Certain of the theories of the origin of cancer which have been proposed in recent years assume that changes in the chromosomes may lead to the production of new races of cells, which possess the capacity of unlimited growth, and large series of studies have been devoted to the investigation of the morphology of the mitotic figures and the number of chromosomes in cells of malignant neoplasms. All of this is excellently surveyed and the reader who

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