[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 585
Citations 0
Comment & Response
November 1, 2016

Mechanisms of Ascites Development

Author Affiliations
  • 1University of Arizona College of Medicine, Tucson
JAMA. 2016;316(17):1828-1829. doi:10.1001/jama.2016.15069

To the Editor Drs Patel and Muir’s JAMA Diagnostic Test Interpretation article1 discussed the evaluation of new-onset ascites, including interpretation of protein and albumin levels in ascitic fluid compared with serum to distinguish among the common causes of ascites—hepatic cirrhosis, heart failure, and peritoneal malignancy. However, their explanation of the underlying pathophysiologic mechanisms in hepatic cirrhosis is not supported by well-substantiated clinical and experimental evidence.2,3

First Page Preview View Large
First page PDF preview
First page PDF preview