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July 14, 1928


Author Affiliations


From the Department of Medicine, University of Rochester School of Medicine and Dentistry.

JAMA. 1928;91(2):78-81. doi:10.1001/jama.1928.02700020012004

In May, 1926, Birkhaug1 reported the results of the treatment of sixty cases of erysipelas with a specific serum. Of these, twelve especially striking cases were reported in detail. The serum was produced by the adaptation of the method which Dochez2 had employed in the production of an immune serum against the streptococcus of scarlet fever. The serum was first employed in the unconcentrated form, of which an average dose of 100 cc. was used, and later in a concentrated form, with an average dose of 15 cc. The report does not state that all recovered, though no specific statement is made that any died, only that "two patients were moribund when first visited." It is impossible to analyze his series of cases from the standpoint of age distribution, seasonal occurrence, total duration of fever and other factors which might enter into an evaluation of the results, nor

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