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Article
November 7, 1942

INCIDENCE OF MALIGNANCY IN PREPYLORIC ULCERS

Author Affiliations

Fellow in Radiology, the Mayo Foundation ROCHESTER, MINN.

JAMA. 1942;120(10):733-735. doi:10.1001/jama.1942.02830450005002
Abstract

The incidence of malignancy in gastric ulcers near the pylorus, long assumed to be disproportionately higher than that of ulcers situated elsewhere in the stomach, has become in recent years an open question. In 1925 Orator1 found in a survey of material at von Eiselsberg's clinic that 30 per cent of prepyloric ulcers were carcinomatous whereas only 2 per cent of ulcers on the lesser curvature in the median portion of the stomach were carcinomatous, and malignancy of duodenal ulcer almost never was observed. In 1929 Haudek2 gave his influential endorsement to Orator's conclusions. Later one of us (B. R. K.),3 who often had heard Carman comment on the frequent occurence of malignancy in prepyloric ulcers, expressed the opinion that ulcers near the pylorus are more likely to be carcinomatous than those on or near the lesser curvature well removed from the pylorus. References could be multiplied

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