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November 7, 1942


JAMA. 1942;120(10):738-740. doi:10.1001/jama.1942.02830450010004

For many years we have been impressed by the fact that cases of duodenal ulcer present a characteristic constitutional psychosomatic pattern. The psychosomatic aspect of disease, with especial reference to its association with duodenal ulceration, has been considered by many authorities as an important contributory factor in the production and intensity of symptoms in peptic ulcer. Psychosomatic phenomena have been strongly emphasized in recent years, although their importance as etiologic factors have not been truly evaluated.

We have undertaken the study of a series of 208 consecutive cases of duodenal ulcer in an effort to correlate any relationship with psychosomatic changes. In this study we have especially noted the general psychoneurologic manifestations and their relation to the activity of the ulcer. We have restricted ourselves to overt manifestations (behavior, emotional attitudes, personality changes) in helping to form our psychosomatic impressions. We have also tried to evaluate the physiologic changes which

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