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Carcinoma of the rectum is a very serious disease; although it may be uncommon in the experience of any individual physician, its early recognition is essential to the life of the patient. Many patients who have carcinoma of the rectum appear at the Mayo Clinic and elsewhere for examination when the local lesion is hopelessly inoperable. This also implies that many of these lesions are beyond even palliative irradiation when first seen. Rankin, in a review of 1,727 cases of malignant disease of the rectum that were observed at the clinic, discovered that only 55 per cent of the lesions were operable and that resection was possible in only 35 per cent. This indicates obviously that in any group of rectal carcinomas the expectancy of life for the patient is short. When it is recalled that carcinoma of the rectum causes definite and annoying symptoms, such as rectal bleeding, pain,
BARGEN JA, LEDDY ET. CARCINOMA OF THE RECTUMSOME CAUSES FOR THE POOR PROGNOSIS. JAMA. 1935;104(14):1201–1203. doi:10.1001/jama.1935.02760140005002