Endovascular thrombectomy is recommended for treatment of severe ischemic stroke caused by large-vessel occlusion in the anterior circulation. Optimal management of sedation and airway during the procedure is controversial. Schönenberger and colleagues assessed the effect of conscious sedation without intubation vs general anesthesia with intubation on early neurological improvement in a randomized open-label clinical trial involving 150 patients undergoing thrombectomy for acute ischemic stroke. The authors found that compared with general anesthesia, use of conscious sedation did not result in greater improvement in neurological status at 24 hours.
Highlights. JAMA. 2016;316(19):1945-1947. doi:10.1001/jama.2015.14588