To the Editor The PARTNER (Partners of People on ART—A New Evaluation of the Risks) study1 reported no documented cases of human immunodeficiency virus (HIV) transmission during condomless sex from stable sexual partners whose HIV infection was suppressed with antiretroviral therapy (ART). In more than 40 000 condomless sex acts during 1238 couple-years of follow-up, 11 incident HIV infections occurred, but none was linked by phylogenetic analysis to the index partner. Rather, these 11 incident HIV infections were transmitted from outside the sexual partnership. We suggest that a more detailed analysis of HIV transmission linkage is necessary.
Goldman JD, Frenkel LM, Mullins JI. HIV Transmission During Condomless Sex With a Seropositive Partner With Suppressed Infection. JAMA. 2016;316(19):2044-2045. doi:10.1001/jama.2016.16030