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Research Letter
November 22/29, 2016

Infectious Disease Mortality Trends in the United States, 1980-2014

Author Affiliations
  • 1University of Arizona, Tucson
  • 2now with Arizona Department of Health Services, Phoenix
JAMA. 2016;316(20):2149-2151. doi:10.1001/jama.2016.12423

From 1900 through 1996, mortality from infectious diseases declined in the United States, except for a 1918 spike due to the Spanish flu pandemic.1 Since 1996, major changes in infectious diseases have occurred, such as the introduction of human immunodeficiency virus (HIV)/AIDS and West Nile virus into the United States, advances in HIV/AIDS treatment, changes in vaccine perceptions, and increased concern over drug-resistant pathogens. We investigated trends in infectious disease mortality from 1980 through 2014 to capture these changes.

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