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Induced by the studies concerning beriberi, vitamin deficiency has been a popular study among Japanese investigators. From of old, cod liver oil has been used in tuberculosis, especially pulmonary tuberculosis. Hence chemists have endeavored to produce its active principle, vitamin A, in pure form and Suzuki and others practically succeeded. More recently Hattori and Matsuura of the Nagoya Sanatorium have studied the clinical effects of cod liver oil and vitamin A, and they suggest that vitamin A is one of the most favorable remedies for use in tuberculosis, but that chemically pure preparations are not as good a remedy as a cruder preparation. At the Institute for Physical and Chemical Studies, antixerophthalmic vitamin A was found to have only indifferent effect against tuberculosis, but xerophthalmia was amenable to the chemically pure preparation of vitamin A. Vitamin B and vitamin C deficiency affected tuberculosis unfavorably.
Censure of Physicians by the
JAPAN. JAMA. 1928;91(6):411. doi:10.1001/jama.1928.02700060045023