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JAMA Clinical Evidence Synopsis
December 27, 2016

Intra-articular Corticosteroids for Osteoarthritis of the Knee

Author Affiliations
  • 1Institute of Primary Health Care, University of Bern, Bern, Switzerland
  • 2Applied Health Research Centre, Li Ka Shing Knowledge Institute of St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada
JAMA. 2016;316(24):2671-2672. doi:10.1001/jama.2016.17565

Clinical Question  Are intra-articular corticosteroids associated with improvement in pain and physical function compared with sham injection or no intervention in patients with knee osteoarthritis?

Bottom Line  Intra-articular corticosteroids may be associated with moderate improvement in pain and a small improvement in physical function up to 6 weeks after injection. However, the quality of the evidence is low.